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GENERIC NAME: fluoxetine hydrochloride
BRAND NAME: Prozac
DRUG CLASS AND MECHANISM: fluoxetine hydrochloride is in a new class of antidepressant
medications that affects chemical messengers within the brain. These chemical
messengers are called neurotransmitters. Many experts believe that an
imbalance in these neurotransmitters is the cause of depression. fluoxetine hydrochloride
is believed to work by inhibiting the release or affects the action of
serotonin. fluoxetine hydrochloride does not have MAO activity.
PRESCRIPTION: Yes
GENERIC AVAILABLE: Yes
PREPARATIONS: Capsules (Pulvules) are available in 10mg and 20mg sizes.
fluoxetine hydrochloride also is available in liquid oral suspension of 20mg/5ml by Dista
labs.
STORAGE: Store in a dry place at 20-25 degrees C (68-77 F).
PRESCRIBED FOR: Depression and has been approved for obsessive compulsive
disorders.
DOSING: fluoxetine hydrochloride is used in the treatment of depression and
obsessive-compulsive disorders. It usually is taken once or twice daily;
however, it also has been taken once weekly. fluoxetine hydrochloride should be taken with
food at doses specifically directed by your physician. Individual doses vary
greatly between individuals. If discontinued you should gradually withdraw
from this medication as directed by your doctor.
DRUG INTERACTIONS: Do not take with MAO inhibitors or for at least two weeks
after their discontinuation. MAO inhibitors medications should not be taken
for at least five weeks after discontinuing fluoxetine hydrochloride (Prozac). The same is
true for Haldol. Most medications affecting the brain have the potential to
slow reflexes or impair judgment and caution is advised. This medication has
not been studied extensively in the US and re-evaluation periodically by your
physician is advised. This medication should not be taken with tryptophan.
Caution when taking this medication with the heart drug lanoxin and the
anticoagulant coumadin. Check with you pharmacist when taking with other
medications.
NURSING MOTHERS: The manufacturer of fluoxetine hydrochloride recommends that women taking
fluoxetine hydrochloride not nurse their infants.
SIDE EFFECTS: fluoxetine hydrochloride as with most antidepressants can cause nausea,
headaches, anxiety, insomnia, drowsiness, and loss of appetite. fluoxetine hydrochloride
has been implicated in serious skin rashes and vasculitis. Increased blood
pressure can occur and should be monitored. Seizures have been reported.
Life-threatening interactions can occur in combination with MAO inhibitors,
such as nardil and parnate. MAO inhibitors and fluoxetine hydrochloride should not be
taken together and a waiting period of 14 days between taking these two
classes of medications is strongly advised.
"If antidepressants are discontinued abruptly, symptoms may occur such as
dizziness, headache, nausea, changes in mood, or changes in the sense of smell,
taste, etc. (Such symptoms even may occur when even a few doses of
antidepressant are missed.) Therefore, it is recommended that the dose of
antidepressant be reduced gradually when therapy is discontinued."
1.
Fluoxetine
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MedlinePlus Drug Information: Fluoxetine
3.
MedlinePlus Drug Information: Fluoxetine (Systemic)
4.
Prozac Online, Description, Chemistry, Ingredients - Fluoxetine ...
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fluoxetine (Prozac) - drug class, medical uses, medication side ...
6.
en.wikipedia.org/wiki/Fluoxetine
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Fluoxetine Information from Drugs.com
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Fluoxetine - Drugs & Vitamins - Drug Library - DrugDigest
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Fluoxetine
10.
PROZAC - Fluoxetine
• Do not stop taking fluoxetine hydrochloride without first talking to your doctor. It may
take several weeks before you to start feeling better.
What is fluoxetine hydrochloride?
• fluoxetine hydrochloride is in a class of drugs called selective serotonin reuptake
inhibitors. fluoxetine hydrochloride affects chemicals in the brain that may become
unbalanced and cause depression or mood disturbances, eating disorders, or
obsessive or compulsive symptoms.
• fluoxetine hydrochloride is used to treat depression, obsessive-compulsive disorders,
panic disorder, and bulimia (binge eating and purging). fluoxetine hydrochloride is also
used to treat premenstrual dysphoric disorder (PMDD), symptoms of which occur
in the week or two before a woman's menstrual period and commonly include
irritability, mood swings, and tension as well as the physical symptoms of
bloating and breast tenderness.
• fluoxetine hydrochloride may also be used for purposes other than those listed in this
medication guide.
What should I discuss with my healthcare provider before taking fluoxetine hydrochloride?
• Do not take fluoxetine hydrochloride if you have taken a monoamine oxidase inhibitor (MAOI)
such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate)
during the last 2 weeks. Serious, and sometimes fatal, reactions have occurred
when these medicines have been used together. Also, do not take fluoxetine hydrochloride
if you are taking thioridazine (Mellaril). Dangerous, even fatal irregular
heartbeats may occur if these medicines are taken together. You must wait 5
weeks after stopping fluoxetine hydrochloride before taking thioridazine (Mellaril).
• Before taking fluoxetine hydrochloride, tell your doctor if you
· have liver disease;
· have kidney disease;
· have diabetes;
· suffer from seizures; or
· suffer from mania or have suicidal thoughts.
• You may not be able to take fluoxetine hydrochloride, or you may need a dosage
adjustment or special monitoring during treatment if you have any of the
conditions listed above.
• fluoxetine hydrochloride is in the FDA pregnancy category C. This means that it is not
known whether fluoxetine hydrochloride will be harmful to an unborn baby. Do not take
fluoxetine hydrochloride without first talking to your doctor if you are pregnant or could
become pregnant during treatment.
• fluoxetine hydrochloride passes into breast milk and may affect a nursing infant. Do not
take fluoxetine hydrochloride without first talking to your doctor if you are
breast-feeding a baby.
How should I take fluoxetine hydrochloride?
• Take fluoxetine hydrochloride exactly as directed by your doctor. If you do not
understand these instructions, ask your pharmacist, nurse, or doctor to
explain them to you.
• Take each dose with water.
• To ensure that you get the correct dose, measure the oral solution with a
dose-measuring cup or spoon, not with a regular table spoon. If you do not
have a dose-measuring device, ask your pharmacist for one.
• fluoxetine hydrochloride may be taken with or without food.
• Try to take fluoxetine hydrochloride at the same time each day.
• Take Prozac Weekly on the same day each week as directed by your doctor.
• Do not stop taking fluoxetine hydrochloride without first talking to your doctor. It may
take several weeks before you to start feeling better.
• Your doctor may want to perform tests or schedule appointments to monitor
your treatment with fluoxetine hydrochloride.
• Store fluoxetine hydrochloride at room temperature away from moisture and heat.